PFE AI Stock Analysis – Buy, Hold, or Avoid?

Pfizer Inc. (PFE)

Fundamentals

Essentia
Essentia
Fundamental Analysis
BULLISH

Pfizer exhibits strong operational performance with steady revenue generation around $60 billion annually and consistent profitability, supported by robust gross margins above 65%. Recent quarters show improving earnings momentum with solid EPS beats, although some volatility in net income is observed due to one-off expenses impacting overall profit. The company maintains a resilient business model with diversified pharmaceutical products driving sustainable growth.

Financial Highlights

Q1 2025Q2 2025Q3 2025Q4 2025Q1 2026-$6.0B$0$6.0B$12.0B$18.0BRevenue & Net Income ($)-10%0%10%20%30%Net Margin (%)
  • Revenue
  • Net Income
  • Net Margin (%)

Revenue

$14.45B

5.37% YoY

Q1 2026

Net Income

$2.69B

-9.40% YoY

Q1 2026

Net Margin

18.60%

Q1 2026

Growth Metrics

Revenue Growth YoY

5.37%

Latest Quarter: Q1 2026

Net Income Growth YoY

-9.40%

Latest Quarter: Q1 2026

Revenue Per Share Growth YoY

5.07%

Latest Quarter: Q1 2026

EPS Growth YoY

-10.10%

Latest Quarter: Q1 2026

Book Value Per Share Growth YoY

-0.54%

Latest Quarter: Q1 2026

 Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024
Revenue14.5B17.6B16.7B14.7B13.7B17.8B17.7B13.3B
Revenue Growth YoY+5.37%-1.16%-5.92%+10.31%-7.82%+21.91%+31.21%+2.12%
Net Income2.7B-1.6B3.5B2.9B3.0B403.0M4.5B24.0M
Net Income Growth YoY-9.40%-508.93%-20.84%+12025.00%-4.90%+112.06%+286.84%-98.97%
EPS$0.47-$0.29$0.62$0.51$0.52$0.07$0.79$0.00
EPS Growth YoY-10.10%-500.55%-21.45%+12042.86%-5.20%+112.14%+286.16%-98.98%

Profitability Metrics

No profitability metrics available

Technical Analysis

Candela
Candela
Technical Analysis
NEUTRAL

Pfizer (PFE) is currently in a technical stage 3 topping phase with mixed signals between a weakening downtrend and short-term bullish patterns. Price action is oscillating around key moving averages, showing indecision with neutral momentum as confirmed by the RSI and ADX indicators. Support near $24.20-$24.50 and resistance around $25.35-$26.00 define the current trading range, with recent pattern formations suggesting potential for modest upside if resistance is reliably broken.

RSI
Hold
Neutral53

No extreme reading

03070100
Trend
Sell
Strong Downtrend

Price in downtrend

-3.1% from 200 SMA
ADX
Hold
Weak/No Trend18

Range-bound market

Weak
MA Cross
Sell
Below 50/200

50 below 200 - bearish

50
200

Key Technical Values

Price
$25.03
50 SMA
$25.07
150 SMA
$26.08
200 SMA
$25.83
52W High
$28.75
52W Low
$23.11

Price with Moving Averages

50-day, 150-day and 200-day simple moving averages

Price
50 SMA
150 SMA
200 SMA

Relative Strength Index

Momentum oscillator measuring speed and magnitude of price changes

RSI (14)

≤30 Oversold
≥70 Overbought
53Neutral

Earnings

Essentia
Essentia
Fundamental Analysis
BULLISH

Pfizer exhibits strong operational performance with steady revenue generation around $60 billion annually and consistent profitability, supported by robust gross margins above 65%. Recent quarters show improving earnings momentum with solid EPS beats, although some volatility in net income is observed due to one-off expenses impacting overall profit. The company maintains a resilient business model with diversified pharmaceutical products driving sustainable growth.

Latest Earnings

Q1 2026 Earnings (Mar 29, 2026)

Earnings Per Share (EPS)

Beat

Actual

$0.75

Estimated

$0.72

Surprise

+$0.03

Surprise %

+3.88%

Revenue

Beat

Actual

$14.45B

Estimated

$13.84B

Surprise

+$610.81M

Surprise %

+4.41%

Historical Earnings

 Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024
Earnings Per Share
EPS (Actual)$0.75$0.66$0.87$0.78$0.92$0.63$1.06$0.60
EPS (Estimated)$0.72$0.57$0.63$0.58$0.67$0.47$0.61$0.46
EPS Surprise+$0.03+$0.09+$0.24+$0.20+$0.25+$0.16+$0.45+$0.14
% Diff+3.9%+16.4%+37.4%+34.5%+38.1%+33.6%+72.6%+31.0%
Revenue
Revenue (Actual)$14.45B$17.56B$16.65B$14.65B$13.72B$17.76B$17.7B$13.28B
Revenue (Estimated)$13.84B$16.85B$16.5B$13.56B$13.92B$17.35B$14.92B$12.96B
Revenue Surprise+$610.81M+$708.08M+$155.9M+$1.09B-$204.75M+$412.57M+$2.78B+$322.05M
% Diff+4.4%+4.2%+0.9%+8.1%-1.5%+2.4%+18.6%+2.5%

Valuation

Valorem
Valorem
Valuation Analysis
FAIRLY VALUED

Pfizer's current valuation reflects a modest premium relative to broader pharmaceutical industry averages but remains attractive compared to some healthcare peers. The company demonstrates stable financial metrics with moderate revenue growth and solid profitability margins, supported by ongoing product pipeline developments and robust cash flow. Analyst consensus leans toward a hold with a moderate upside potential based on cautiously optimistic earnings forecasts and pipeline progress.

Valuation Metrics

Price to Earnings

19.12

TTM

Price to Sales

2.25

TTM

Price to Book

1.58

TTM

Enterprise Value to EBITDA

12.27

TTM

Enterprise Value to Revenue

3.25

TTM

 Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024
Price to Earnings14.77-21.479.6211.8812.1291.619.171679.76
Price to Sales10.948.068.149.4010.498.469.2612.04
Price to Book1.751.641.461.551.591.701.781.82
Enterprise Value to EBITDA43.97274.8334.6937.1940.2841.4131.6594.60
Enterprise Value to Revenue15.2811.8311.7713.5114.8511.9912.9717.13

Sentiment & Analyst Ratings

Pulse
Pulse
Sentiment Analysis
MIXED

Pfizer's market sentiment is cautiously optimistic amid mixed financial signals. While Q2 2026 earnings estimates reflect a slight decline year-over-year, the company benefits from pipeline progress in oncology and vaccines, alongside a strong dividend yield that appeals to value investors. Analysts largely maintain a Hold rating with price targets around $28-$29, indicating moderate upside potential despite risks around patent expirations and recent CFO departure.

Analyst Recommendations

As of Aug 1, 2026
Strong SellSellHoldBuyStrong Buy
Hold
3.3 / 5.0
Based on 28 analyst ratings
Strong Sell
1
Sell
1
Hold
16
Buy
8
Strong Buy
2

Risk Assessment

Sentinel
Sentinel
Risk Assessment
MODERATE

Pfizer (PFE) currently exhibits a moderate financial risk profile characterized by adequate liquidity ratios and manageable leverage. However, the company faces significant near-term challenges from legal litigations, patent expirations, and revenue declines in its COVID-19 products, coupled with a pipeline visible lag, which heighten uncertainty for future growth and dividend sustainability.

Liquidity & Solvency

Frequently Asked Questions about PFE

AI Answers: Common Questions About PFE

Get AI-powered answers to the questions investors ask most about Pfizer Inc.

Pfizer is a good long-term buy given its low P/E of 8.17, strong margins (65-70% gross margin), and steady revenue growth (~3-5% annually). However, short-term technical signals suggest holding until clearer momentum emerges.

There is no strong sell signal currently. Risks from patent expirations and legal issues exist, but fundamentals and valuation support holding or accumulating on dips rather than selling outright.

Key risks include patent cliffs on blockbuster drugs, ongoing litigation (e.g., Depo-Provera), and declining COVID-19 vaccine revenues, which could pressure earnings and dividends.

Analyst price targets range around $28-$29, implying moderate upside from the current price of $25.01, supported by pipeline progress and earnings recovery.

Pfizer is fairly valued with a P/E of 8.17, slightly above industry averages but justified by steady earnings and pipeline prospects. Price-to-book ratio indicates undervaluation relative to assets.

Strong fundamentals include $63-$64 billion annual revenue, gross margins above 65%, operating margins near 25%, and improving EPS growth (~24% YoY in latest quarter).

Technically, Pfizer is in a neutral to bearish phase with resistance at $25.35-$26.00 and support at $24.20-$24.50. Momentum indicators like RSI (~52) and ADX (~17.6) show weak trend strength, suggesting consolidation.

Upcoming catalysts include pipeline product approvals, positive earnings surprises, regulatory decisions, and resolution of legal issues, which could drive stock performance.

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