PFE AI Stock Analysis – Buy, Hold, or Avoid?
Pfizer Inc. (PFE)
Fundamentals
Pfizer exhibits strong operational performance with steady revenue generation around $60 billion annually and consistent profitability, supported by robust gross margins above 65%. Recent quarters show improving earnings momentum with solid EPS beats, although some volatility in net income is observed due to one-off expenses impacting overall profit. The company maintains a resilient business model with diversified pharmaceutical products driving sustainable growth.
Financial Highlights
- Revenue
- Net Income
- Net Margin (%)
Revenue
5.37% YoY
Q1 2026
Net Income
-9.40% YoY
Q1 2026
Net Margin
Q1 2026
Growth Metrics
Revenue Growth YoY
Latest Quarter: Q1 2026
Net Income Growth YoY
Latest Quarter: Q1 2026
Revenue Per Share Growth YoY
Latest Quarter: Q1 2026
EPS Growth YoY
Latest Quarter: Q1 2026
Book Value Per Share Growth YoY
Latest Quarter: Q1 2026
| Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | |
|---|---|---|---|---|---|---|---|---|
| Revenue | 14.5B | 17.6B | 16.7B | 14.7B | 13.7B | 17.8B | 17.7B | 13.3B |
| Revenue Growth YoY | +5.37% | -1.16% | -5.92% | +10.31% | -7.82% | +21.91% | +31.21% | +2.12% |
| Net Income | 2.7B | -1.6B | 3.5B | 2.9B | 3.0B | 403.0M | 4.5B | 24.0M |
| Net Income Growth YoY | -9.40% | -508.93% | -20.84% | +12025.00% | -4.90% | +112.06% | +286.84% | -98.97% |
| EPS | $0.47 | -$0.29 | $0.62 | $0.51 | $0.52 | $0.07 | $0.79 | $0.00 |
| EPS Growth YoY | -10.10% | -500.55% | -21.45% | +12042.86% | -5.20% | +112.14% | +286.16% | -98.98% |
Profitability Metrics
Technical Analysis
Pfizer (PFE) is currently in a technical stage 3 topping phase with mixed signals between a weakening downtrend and short-term bullish patterns. Price action is oscillating around key moving averages, showing indecision with neutral momentum as confirmed by the RSI and ADX indicators. Support near $24.20-$24.50 and resistance around $25.35-$26.00 define the current trading range, with recent pattern formations suggesting potential for modest upside if resistance is reliably broken.
No extreme reading
Price in downtrend
Range-bound market
50 below 200 - bearish
Key Technical Values
Price with Moving Averages
50-day, 150-day and 200-day simple moving averages
Relative Strength Index
Momentum oscillator measuring speed and magnitude of price changes
RSI (14)
Earnings
Pfizer exhibits strong operational performance with steady revenue generation around $60 billion annually and consistent profitability, supported by robust gross margins above 65%. Recent quarters show improving earnings momentum with solid EPS beats, although some volatility in net income is observed due to one-off expenses impacting overall profit. The company maintains a resilient business model with diversified pharmaceutical products driving sustainable growth.
Latest Earnings
Q1 2026 Earnings (Mar 29, 2026)
Earnings Per Share (EPS)
Actual
$0.75
Estimated
$0.72
Surprise
+$0.03
Surprise %
+3.88%
Revenue
Actual
$14.45B
Estimated
$13.84B
Surprise
+$610.81M
Surprise %
+4.41%
Historical Earnings
| Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | |
|---|---|---|---|---|---|---|---|---|
| Earnings Per Share | ||||||||
| EPS (Actual) | $0.75 | $0.66 | $0.87 | $0.78 | $0.92 | $0.63 | $1.06 | $0.60 |
| EPS (Estimated) | $0.72 | $0.57 | $0.63 | $0.58 | $0.67 | $0.47 | $0.61 | $0.46 |
| EPS Surprise | +$0.03 | +$0.09 | +$0.24 | +$0.20 | +$0.25 | +$0.16 | +$0.45 | +$0.14 |
| % Diff | +3.9% | +16.4% | +37.4% | +34.5% | +38.1% | +33.6% | +72.6% | +31.0% |
| Revenue | ||||||||
| Revenue (Actual) | $14.45B | $17.56B | $16.65B | $14.65B | $13.72B | $17.76B | $17.7B | $13.28B |
| Revenue (Estimated) | $13.84B | $16.85B | $16.5B | $13.56B | $13.92B | $17.35B | $14.92B | $12.96B |
| Revenue Surprise | +$610.81M | +$708.08M | +$155.9M | +$1.09B | -$204.75M | +$412.57M | +$2.78B | +$322.05M |
| % Diff | +4.4% | +4.2% | +0.9% | +8.1% | -1.5% | +2.4% | +18.6% | +2.5% |
Valuation
Pfizer's current valuation reflects a modest premium relative to broader pharmaceutical industry averages but remains attractive compared to some healthcare peers. The company demonstrates stable financial metrics with moderate revenue growth and solid profitability margins, supported by ongoing product pipeline developments and robust cash flow. Analyst consensus leans toward a hold with a moderate upside potential based on cautiously optimistic earnings forecasts and pipeline progress.
Valuation Metrics
Price to Earnings
TTM
Price to Sales
TTM
Price to Book
TTM
Enterprise Value to EBITDA
TTM
Enterprise Value to Revenue
TTM
| Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | |
|---|---|---|---|---|---|---|---|---|
| Price to Earnings | 14.77 | -21.47 | 9.62 | 11.88 | 12.12 | 91.61 | 9.17 | 1679.76 |
| Price to Sales | 10.94 | 8.06 | 8.14 | 9.40 | 10.49 | 8.46 | 9.26 | 12.04 |
| Price to Book | 1.75 | 1.64 | 1.46 | 1.55 | 1.59 | 1.70 | 1.78 | 1.82 |
| Enterprise Value to EBITDA | 43.97 | 274.83 | 34.69 | 37.19 | 40.28 | 41.41 | 31.65 | 94.60 |
| Enterprise Value to Revenue | 15.28 | 11.83 | 11.77 | 13.51 | 14.85 | 11.99 | 12.97 | 17.13 |
Sentiment & Analyst Ratings
Pfizer's market sentiment is cautiously optimistic amid mixed financial signals. While Q2 2026 earnings estimates reflect a slight decline year-over-year, the company benefits from pipeline progress in oncology and vaccines, alongside a strong dividend yield that appeals to value investors. Analysts largely maintain a Hold rating with price targets around $28-$29, indicating moderate upside potential despite risks around patent expirations and recent CFO departure.
Analyst Recommendations
Risk Assessment
Pfizer (PFE) currently exhibits a moderate financial risk profile characterized by adequate liquidity ratios and manageable leverage. However, the company faces significant near-term challenges from legal litigations, patent expirations, and revenue declines in its COVID-19 products, coupled with a pipeline visible lag, which heighten uncertainty for future growth and dividend sustainability.
Liquidity & Solvency
Frequently Asked Questions about PFE
AI Answers: Common Questions About PFE
Get AI-powered answers to the questions investors ask most about Pfizer Inc.
Pfizer is a good long-term buy given its low P/E of 8.17, strong margins (65-70% gross margin), and steady revenue growth (~3-5% annually). However, short-term technical signals suggest holding until clearer momentum emerges.
There is no strong sell signal currently. Risks from patent expirations and legal issues exist, but fundamentals and valuation support holding or accumulating on dips rather than selling outright.
Key risks include patent cliffs on blockbuster drugs, ongoing litigation (e.g., Depo-Provera), and declining COVID-19 vaccine revenues, which could pressure earnings and dividends.
Analyst price targets range around $28-$29, implying moderate upside from the current price of $25.01, supported by pipeline progress and earnings recovery.
Pfizer is fairly valued with a P/E of 8.17, slightly above industry averages but justified by steady earnings and pipeline prospects. Price-to-book ratio indicates undervaluation relative to assets.
Strong fundamentals include $63-$64 billion annual revenue, gross margins above 65%, operating margins near 25%, and improving EPS growth (~24% YoY in latest quarter).
Technically, Pfizer is in a neutral to bearish phase with resistance at $25.35-$26.00 and support at $24.20-$24.50. Momentum indicators like RSI (~52) and ADX (~17.6) show weak trend strength, suggesting consolidation.
Upcoming catalysts include pipeline product approvals, positive earnings surprises, regulatory decisions, and resolution of legal issues, which could drive stock performance.
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